Zembrace is an excellent remedy to relieve an acute migraine attack. It is very popular with migraine sufferers. But like any drug, it requires careful handling.
If you decide to try it, be sure to check out the side effects Zembrace has.
Zembrace side effects
General symptoms: pain, tingling, hot sensation, feeling of pressure or heaviness (these symptoms are usually transient but can be intense and occur in any part of the body, including the chest and throat), hot flashes, dizziness, feeling weak and / or tired. drowsiness (usually mild to moderate and transient).
From the side of the cardiovascular system: arterial hypotension, bradycardia, tachycardia (including ventricular), palpitations, a temporary increase in blood pressure (observed shortly after taking sumatriptan); there are rare reports of cardiac arrhythmias (up to fibrillation), transient ischemic ECG changes, myocardial infarction, coronary artery spasm; sometimes Raynaud’s syndrome develops.
From the gastrointestinal tract: some patients experienced nausea and vomiting (the relationship of these side effects with the intake of sumatriptan has not been established); a slight increase in the activity of liver enzymes, dysphagia, a feeling of discomfort in the abdomen; rarely – ischemic colitis.
From the side of the central nervous system and the organ of vision: there are some rare reports of seizures after taking sumatriptan. In some cases, they were observed in patients with a history of seizures or in conditions that predispose to seizures; in some patients, no predisposing factors were identified. Sometimes, after taking Zembrace SymTouch, diplopia, flickering in the eyes, nystagmus, scotoma, and decreased visual acuity were noted. Partial transient loss of vision was extremely rare. However, it should be borne in mind that visual impairment may be associated with the migraine attack itself.
Hypersensitivity reactions: skin manifestations (rash, urticaria, pruritus, erythema); in rare cases, anaphylaxis.
Local symptoms (when using the spray): mild transient irritation or burning sensation in the nasal cavity or pharynx, nosebleeds.
Feeling of tingling, warmth, heaviness, pressure in various parts of the body, hyperemia of the skin and mucous membranes; dizziness, tiredness, weakness, drowsiness; an attack of angina pectoris, hypotension, tachycardia, palpitations, transient increase in blood pressure, transient ECG changes of the ischemic type, bradycardia, in rare cases – Raynaud’s syndrome; feeling of discomfort in the abdomen, dysphagia, nausea, vomiting, ischemic colitis; visual impairment (diplopia, scotoma, decreased visual acuity); allergic reactions (rash, urticaria, pruritus, erythema, anaphylaxis); changes in liver function tests; myalgia.
Depending on the frequency of occurrence, the following groups of side effects are distinguished: very often – ≥1 / 10; often – ≥1 / 100, <1/10; infrequently – ≥1 / 1000, <1/100; rarely – ≥1 / 10000, <1/1000; very rarely – <1/10000, including isolated cases; frequency unknown – incidence cannot be estimated from the available data.
From the nervous system: often – dizziness, drowsiness, sensory disturbances, including paresthesia and hypesthesia; the frequency is unknown – seizures (in some cases they were observed in patients with a history of seizures or in conditions that predispose to the occurrence of seizures; in some patients, no predisposing factors were identified), tremor, dystonia, anxiety.
From the side of the organ of vision: the frequency is unknown – diplopia, flickering before the eyes, decreased visual acuity, partial transient or persistent loss of vision, nystagmus, scotoma. However, it should be borne in mind that visual impairment may be associated with the migraine attack itself.
From the CVS: often – a transient increase in blood pressure (observed shortly after taking sumatriptan), hot flashes; the frequency is unknown – bradycardia, tachycardia, decreased blood pressure, heart rhythm disturbances, transient ECG changes in ischemic type, myocardial infarction, coronary artery spasm, angina pectoris, Raynaud’s syndrome, palpitations.
From the digestive tract: often – nausea, vomiting; very rarely – dysphagia, a feeling of discomfort in the abdomen; frequency unknown – ischemic colitis, diarrhea.
From the musculoskeletal system: often – myalgia; infrequently – joint pain; frequency unknown – stiff neck.
On the part of the respiratory system and chest organs: often – shortness of breath, slight transient irritation of the mucous membrane or a burning sensation in the nasal cavity or throat, nosebleeds.
Laboratory indicators: very rarely – slight changes in the activity of hepatic transaminases.
Allergic reactions: very rare – hypersensitivity reactions range from skin manifestations (rash, urticaria, pruritus, erythema) to cases of anaphylaxis.
On the part of the skin and subcutaneous tissue: the frequency is unknown – hyperhidrosis.
Others: often – a feeling of heat or cold, pain, a feeling of pressure or heaviness (they are transient and can occur in any part of the body, including the chest and throat), a feeling of weakness, a feeling of fatigue, usually mild or moderate and having a transient nature. There may be transient intense pain and chest tightness extending to the neck.